Dr. Tom Crandall, a clinical psychologist, is awakened late one night by a telephone call. The call was from his brother Nick who is addicted to drugs. Dr. Crandall knew things did not sound good and he had to get to Nick as soon as possible.
When he found Nick, Dr. Crandall witnessed a very bizarre behavior by his brother. Nick kept saying that worms were inside his brain. Dr. Crandall tried to do everything possible to calm down Nick but before he could stop him, Nick goes over the cliff and lands in the water. What is going on with Nick? Test results show some drugs present but they are not the type of results Tom expected.
Many strange things start to happen including Paul, Tom’s brother, allowing a movie company to build a set on one of their properties and threats to Tom’s family. The movie producer is a scientist who is rather bizarre. Could there be some connection between this movie company and what happened to Nick?